Susceptibility of autoimmune diseases in three polymorphisms of infection-associated gene IRAK1
Introduction: Infection of pathogenic microorganisms here is an important reason for autoimmune diseases (ADs).Interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK1) is a key mediator in infection immunity, while the gene of IRAK1 is recognized as a risk gene in ADs.Three single nucleotide polymorphisms (SNPs) in IRAK1 (rs3027898, rs1059702, rs1